Why Genetic Testing?
Can your genes affect the way you respond to medicine, food and exercise? Science says yes. When you understand your genetic predispositions, you gain powerful insight that can be used to target solutions shown effective for people like you. No more one size fits all approach to the medicines you take, mitigation of cancer risk, and even weight loss; let’s find what works for YOU.
One of the great promises of genetic testing is personalized medicine – allowing physicians to deliver health care based on a person’s genotype. An individual’s genetics can suggest optimal dosing levels, cause some medications to be more or less effective, or in some cases lead to avoiding wrong medications that could cause personal harm.
We offer a targeted Mental Health DNA panel to identify genetic variants that affect the metabolism and efficacy of psychiatric medications. Genetic research suggests that categorizing individuals based on genotypes will make the pharmacologic treatment of psychiatric illnesses more predictable and effective. Mental Health DNA Insight can help predict your response to more than 40 common antidepressants, mood stabilizers and antipsychotic medications. The report provides outcomes in a clear color-coded chart.
What works for one, may not work for another. The Pain Medication DNA panel identifies genetic variants that affect how an individual will respond to the analgesic effects of certain types of commonly prescribed pain medications. Personalized medication management is essential in identifying the right drug and dosage.
You need to understand how YOU lose weight
Clinical studies have shown that individuals who follow a genetically appropriate diet lose weight more easily. We can analyze over 75 genetic markers known to impact metabolism, exercise and energy use within the human body. Through the examination of these genetic markers, which are expressed in various organs such as the brain, stomach, gut, muscle, pancreas, as well as directly in fat tissue, we are able to gain an insight into how a person’s body processes sugars, fats, and nutrients and vitamins. What’s more, our report includes detailed analysis on how your body responds to exercise and performance, and provides strategies to help you reach an optimal potential to maintain a healthy weight based on your specific genetics.
What is MTHFR?
MTHFR (Methyl-TetraHydroFolate Reductase) is a common genetic issue that can lead to a variety of medical problems because the methylation process (responsible for cellular repair, detoxification, and a healthy immune system) can be reduced by as much as 40%. While many of us carry one mutation, the effect of it is often masked due to the prevalence of fortified food in the US. Those with two mutations will often struggle with many of the medical issues below. Click here to find out more.
Among women, breast cancer is the second leading cause of cancer death. One in eight women will be affected by breast cancer in their lifetime. Recent studies of breast cancer survivors have shown that approximately 70 percent of the mutations identified were BRCA1/2 mutations. Approximately 4 percent had germline mutations in other cancer-susceptibility genes, including high-risk genes. These additional high-risk genes include CDH1, PALB2, PTEN, STK11, and TP53.
Our panel is done through a blood or saliva sequencing test with deletion/duplication analysis to detect mutations in up to seven high-risk breast cancer susceptibility genes, including BRCA1, BRCA2 and PALB2.
Approximately 25 percent of all cases of colorectal cancers can be attributed to heritable genetic changes. Based on a saliva or blood sample, we use next-generation sequencing (NGS) technology to identify genetic changes that increase a patient’s risk of developing certain types of cancer.
An estimated 1.6 million Americans will be diagnosed with cancer in 2013. More than half of all cancer deaths are estimated to be from preventable risks. Obesity, diet and exercise combined can be linked to almost 30% of the preventable causes. Through genetic testing we are able to make patient-specific recommendations to reduce the risk of cancer.
Insight that leads to better choices
Through your genetics, we can examines eight classes of drugs that affect the cardiovascular system: anti-platelets, anti-coagulants, statins, stimulants, beta-blockers, ACE inhibitors, calcium channel blockers and hormone therapies. This insight may be used to enhance the information provided in lipid tests that evaluate risk for cardiovascular disease.
Further, we can understand how your genetics and lifestyle affect diet, nutrition, weight and overall heart health.
Clinical studies have shown that individuals who follow a genetically appropriate diet lose significantly more weight and are able to maintain weight loss more easily than those on a diet not based on their genetics.
How are your children at risk?
We can screen for more than 70 recessive genetic diseases providing relevant genetic insights about the health of your future children. By following the American College of Obstetricians and Gynecologists (ACOG) recommendations, we offer a comprehensive preconception and prenatal carrier screening test.
Recent advances in medical research have identified genetic markers associated with many complex health conditions. We can screens for genetic markers that identify your propensity for developing common health conditions. Having these genetic markers does not mean you will get the disease, but it does indicate whether you may have an increased or decreased risk of developing the condition. The following are conditions included in this screening:
- Age-related macular degeneration
- Alzheimer’s disease, late onset
- Amyotrophic lateral sclerosis (sporadic)
- Atrial fibrillation
- Breast cancer (females only)
- Colorectal cancer
- Coronary artery disease
- Diabetes, type 1
- Diabetes, type 2
- Exfoliation glaucoma
- Leukemia, chronic lymphocytic
- Lung cancer
- Multiple sclerosis
- Myocardial infarction
- Parkinson’s disease
- Peripheral arterial disease
- Prostate cancer (males only)
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Ulcerative colitis